Mr. Wander is a 61-year-old gentleman with past stroke without sequelae, hepatitis C virus (HCV) infection not on treatment, HIV diagnosed at age 37 on efavirenz, tenofovir and emtricitabine, who presents to the emergency room stating “a man who takes care of horses” gave him a pill which made him ill. He denies other specific complaints or symptoms. He reports that he takes “approximately 4 medications daily” but is unable to elaborate the name, dosage and timing of any of his medications. His last CD4 is 170 cells/mm3 and his viral load is undetectable. He has prior meningoencephalitis due to toxoplasmosis.