Journal Article

Hypertension, Diabetes, Neuropathy Higher in Overweight HIV Adult Patients

The risk for being obese or overweight was assessed using a sample of 862 patients in France (median age 51 years; 68% male; on ART for 16.7 years median; 91% had undetectable viral loads; 73% had CD4 counts of 500 or greater; 31% had HCV serology with 13% having detectable HCV-RNA; 60% were smokers). Obesity (>/=30 kg/m) was observed in 5% of the sample, and overweight (>/ 25= kg/m; <30 kg/m) affected 22% of the patients. Almost 36% had at least one comorbidity. Of these almost 53% were overweight or obese. The prevalence of hypertension, diabetes, and peripheral arteriopathy was significantly higher among overweight patients. The prevalence of acute myocardial infarction was significantly higher in patients who were overweight. The data reported found that aging, gender (male), alcohol consumption, absence of active HCV coinfection and tobacco use, but not ART regimen or CD4+ T cell count, are associated with overweight and/or obesity in this HIV cohort. Increasing rates of obesity and being overweight are being observed in multiple studies. These increases are associated with elevating the risk for multimorbidity.

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