HIV & Aging: Journal Articles

Cognitive impairment and carotid artery stiffness characterize many older adults with HIV. A risk for Alzheimer’s disease may be poor blood flow to the brain.

Those with HIV have an increased risk of cardiovascular disease. A study using CT (computed tomography) compared those with and without HIV for the frequency of calcium deposits in coronary artery plaques.

Each year we collect the published articles that address the topic of older adults living with HIV/AIDS.
The number is again higher this year and are about 1000 in number.

Previous studies have shown that cabotegravir and rilpivirine (Cabenuva) injections every 4 weeks provided a similar result to oral ART therapy. This regimen has received FDA approval.  The question is whether a longer period between injections is possible.

CGA is defined as a multidisciplinary diagnostic and treatment process that evaluates medical, psychosocial, and functional deficits in order to develop a coordinated intervention/plan to maximize overall health with aging.

Every two years a group of recognized experts updates a document on recommended antiretroviral drugs for treatment and prevention of HIV . This year’s edition provides a detailed review of the most recent recommendation collected from over 500 sources.

For a number of years HRSA has sponsored the Ryan White HIV/AIDS Program. The funding has focused on HIV management, specifically achieving sustained viral load suppression.  It has been very successful by not only addressing medical issues but also “Wraparound Services” such as  housing, nutrition, case management etc. 

In a study from Madrid 77,590 HIV-positive persons on antiretroviral therapy (ART) were followed for outcomes over 75 days. Of this group, 236 developed documented COVID-19, and 151 were hospitalized.

In a cohort study in New York City 30 hospitalized people living with HIV (PLWH) were compared to 90 similar patients without HIV for effects of COVID-19.

A study from Germany describes the experience of  33 people living with HIV and COVID-19. Just over 90% of the patients recovered with 76% classified as mild. However, 9% died. This frequency of death was higher than the German average of 4%.


Purpose of this Program: The AAHIVM, ACRIA and AGS (collectively, the “Sponsors,” “we” or “us”) are sponsors of this Website and through it seek to address the unique needs and challenges that older adults of diverse populations living with HIV face as they age. However, the information in this Website is not meant to supplant the advice provided in a doctor-patient relationship.

General Disclaimer: is designed for educational purposes only and is not engaged in rendering medical advice or professional services. The information provided through should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem, consult your health care provider.



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The American Academy of HIV Medicine is a professional organization that supports the HIV practitioner and promotes accessible, quality care for all Americans living with HIV disease. Our membership of HIV practitioners and credentialed HIV Specialists™, HIV Experts™, and HIV Pharmacists™ provide direct care to the majority of HIV patients in the US.