Aging

As part of stroke prevention, especially with vascular symptoms, carotid endarterectomy or carotid stenting are often performed.

Increased vascular stiffness has been found in adults with HIV. A key question is if the vascular stiffness is related to cognitive decline.

With mortality from HIV reduced there are more older persons living with HIV. The concern is that diseases and conditions associated with aging will become frequent and result in multimorbidity (MM) in this subgroup.

The question addressed by this report is whether the frequency of multimorbidity (MM) is increasing over time as persons with HIV continue to age.

An important question is the effect of unmet basic needs, such as food security and stable housing, on persons with HIV. A study to address this question is reported using a cohort of 496 adults with HIV living in Ontario, Canada.

With better HIV treatment, the frequency of Herpes Zoster (HZ) in older adults with HIV has dropped but is still at least two to three times higher than in persons uninfected with HIV.

There is variability in reports about the presence of an increased frequency of diabetes mellitus (DM) in older persons with HIV. Most suggest an excess than in a comparison group, but the reasons for this increase are unclear.

The latest (2016) HIV frequency estimate from CDC indicates that two thirds of infections have involved male-to-male sexual contact.

The FDA approved PrEP (tenofovir and emtricitabine) as a once a day single pill in 2012. Since 2014 the CDC has recommended this form of PrEP because it was found to be safe and very effective in the prevention of HIV in high-risk populations.

The average age for older adults with HIV is increasing. There is interest in identifying predictors of mortality outcomes as a guide to better management and to identify possible reversible risk factors.